BDBM50115967 2-[(3,5-Bis-trifluoromethyl-benzoyl)-methyl-amino]-4'-chloro-biphenyl-4-carboxylic acid hydroxy-methyl-amide::CHEMBL62649

SMILES CN(O)C(=O)c1ccc(-c2ccc(Cl)cc2)c(c1)N(C)C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=BSFVUCOLFARLEH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50115967   

TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115967(2-[(3,5-Bis-trifluoromethyl-benzoyl)-methyl-amino]...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity was determined by measuring the inhibition of 125 I-NKA binding to transfected CHO-cells expressing human recombinant Tachykinin rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115967(2-[(3,5-Bis-trifluoromethyl-benzoyl)-methyl-amino]...)
Affinity DataIC50:  0.600nMAssay Description:inhibition of [3H]-Sar-SP binding to Tachykinin receptor 1 of bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed