BDBM50115970 4'-Chloro-2-(3,4,5-trimethoxy-benzoylamino)-biphenyl-4-carboxylic acid cyclohexylamide::CHEMBL62341::N-[4'-Chloro-4-(2-cyclohexylamino-acetyl)-biphenyl-2-yl]-3,4,5-trimethoxy-benzamide

SMILES COc1cc(cc(OC)c1OC)C(=O)Nc1cc(ccc1-c1ccc(Cl)cc1)C(=O)NC1CCCCC1

InChI Key InChIKey=JSSIHFUHGXNMHG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50115970   

TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115970(4'-Chloro-2-(3,4,5-trimethoxy-benzoylamino)-biphen...)
Affinity DataIC50:  30nMAssay Description:Binding affinity was determined by measuring the inhibition of 125 I-NKA binding to transfected CHO-cells expressing human recombinant Tachykinin rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115970(4'-Chloro-2-(3,4,5-trimethoxy-benzoylamino)-biphen...)
Affinity DataIC50:  30nMAssay Description:Binding affinity towards tachykinin receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50115970(4'-Chloro-2-(3,4,5-trimethoxy-benzoylamino)-biphen...)
Affinity DataIC50:  9nMAssay Description:Inhibitory concentration against neurokinin NK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50115970(4'-Chloro-2-(3,4,5-trimethoxy-benzoylamino)-biphen...)
Affinity DataIC50:  9nMAssay Description:inhibition of [3H]-Sar-SP binding to Tachykinin receptor 1 of bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed