BDBM50116050 1-(4-Carboxymethyl-7-nitro-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin-6-yl)-1H-pyrrole-3-carboxylic acid::CHEMBL293613

SMILES OC(=O)Cn1c2cc(c(cc2[nH]c(=O)c1=O)[N+]([O-])=O)-n1ccc(c1)C(O)=O

InChI Key InChIKey=MLIKVWYGUKDINC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50116050   

TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116050(1-(4-Carboxymethyl-7-nitro-2,3-dioxo-1,2,3,4-tetra...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116050(1-(4-Carboxymethyl-7-nitro-2,3-dioxo-1,2,3,4-tetra...)
Affinity DataKi:  4.10E+3nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116050(1-(4-Carboxymethyl-7-nitro-2,3-dioxo-1,2,3,4-tetra...)
Affinity DataKi:  5.80E+3nMAssay Description:Binding affinity for human GluR6 expressed in HEK-293 cells using [3]H-kainateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116050(1-(4-Carboxymethyl-7-nitro-2,3-dioxo-1,2,3,4-tetra...)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity of the compound was determined towards Kai-2 using [3]H-kainate as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed