BDBM50116213 4-((S)-2-Azetidin-2-yl-ethoxy)-7-chloro-2-oxo-3-(3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid pyrimidin-2-ylamide::CHEMBL71561

SMILES Cc1cc(cc(C)c1C)-c1c(OCC[C@@H]2CCN2)c2cc(C(=O)Nc3ncccn3)c(Cl)cc2[nH]c1=O

InChI Key InChIKey=DBDBBVLTWXUUQH-IBGZPJMESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50116213   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50116213(4-((S)-2-Azetidin-2-yl-ethoxy)-7-chloro-2-oxo-3-(3...)
Affinity DataIC50:  0.440nMAssay Description:Ability of compound to inhibit [I125-Tyr5,DLeu6,NMeLeu7,Pro9-NEt]GnRH agonist binding to the cloned human Gonadotropin-releasing hormone receptor was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50116213(4-((S)-2-Azetidin-2-yl-ethoxy)-7-chloro-2-oxo-3-(3...)
Affinity DataIC50:  4nMAssay Description:Ability of compound to inhibit [I125-Tyr5,DLeu6,NMeLeu7,Pro9-NEt]GnRH agonist binding to the rat Gonadotropin-releasing hormone receptor was evaluate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed