BDBM50117461 3-[3-(3-Acetyl-phenyl)-ureido]-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-N-methyl-benzamide::CHEMBL123611

SMILES CNC(=O)c1cccc(NC(=O)Nc2cccc(c2)C(C)=O)c1CN1CCC(Cc2ccc(F)cc2)CC1

InChI Key InChIKey=AYLIGBDQTHFVLJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50117461   

TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50117461(3-[3-(3-Acetyl-phenyl)-ureido]-2-[4-(4-fluoro-benz...)
Affinity DataIC50:  30nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50117461(3-[3-(3-Acetyl-phenyl)-ureido]-2-[4-(4-fluoro-benz...)
Affinity DataIC50:  1nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50117461(3-[3-(3-Acetyl-phenyl)-ureido]-2-[4-(4-fluoro-benz...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against recombinant human Chemokine receptor type 3 (CCR3) expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed