BDBM50117717 3-Isobutyl-8-(2-isopropoxy-phenyl)-1-methyl-3,7-dihydro-purine-2,6-dione::CHEMBL314667

SMILES CC(C)Cn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccccc1OC(C)C

InChI Key InChIKey=LABTVQUPSPQYOL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50117717   

TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50117717(3-Isobutyl-8-(2-isopropoxy-phenyl)-1-methyl-3,7-di...)
Affinity DataIC50:  214nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50117717(3-Isobutyl-8-(2-isopropoxy-phenyl)-1-methyl-3,7-di...)
Affinity DataIC50:  77nMAssay Description:Inhibitory activity against human platelet Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed