BDBM50118233 2'-deoxyadenosine 5'-(tetrahydrogen triphosphate)::ATP,2'-deoxy::CHEMBL335538::dATP

SMILES Nc1ncnc2n(cnc12)[C@H]1C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O1

InChI Key InChIKey=SUYVUBYJARFZHO-UHFFFAOYSA-N

Data  2 KI  6 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50118233   

TargetP2Y purinoceptor 1(Wild turkey)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118233(CHEMBL335538 | dATP | ATP,2'-deoxy | 2'-deoxya...)
Affinity DataEC50:  1.90E+4nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 11(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118233(CHEMBL335538 | dATP | ATP,2'-deoxy | 2'-deoxya...)
Affinity DataEC50:  9.00E+3nMAssay Description:The compound was evaluated for antagonist activity against phospholipase C coupled human P2Y purinoceptor 11 (P2Y11)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Pittsburgh School of Medicine

Curated by ChEMBL
LigandPNGBDBM50118233(CHEMBL335538 | dATP | ATP,2'-deoxy | 2'-deoxya...)
Affinity DataKd:  3.20E+3nMAssay Description:Binding affinity to HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50118233(CHEMBL335538 | dATP | ATP,2'-deoxy | 2'-deoxya...)
Affinity DataKd:  6.60E+3nMAssay Description:Binding affinity to HIV1 reverse transcriptase K65R mutant by pre-steady state kinetics studyMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Pittsburgh School of Medicine

Curated by ChEMBL
LigandPNGBDBM50118233(CHEMBL335538 | dATP | ATP,2'-deoxy | 2'-deoxya...)
Affinity DataKd:  4.60E+3nMAssay Description:Binding affinity to wild type HIV1 reverse transcriptase by pre-steady state kinetics studyMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50118233(CHEMBL335538 | dATP | ATP,2'-deoxy | 2'-deoxya...)
Affinity DataKd:  2.50E+3nMAssay Description:Binding affinity to HIV1 reverse transcriptase M184V mutant assessed as L-3'-azido-NTP incorporation in nascent DNAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Pittsburgh School of Medicine

Curated by ChEMBL
LigandPNGBDBM50118233(CHEMBL335538 | dATP | ATP,2'-deoxy | 2'-deoxya...)
Affinity DataKd:  3.20E+3nMAssay Description:Binding affinity to HIV1 reverse transcriptase assessed as L-3'-azido-NTP incorporation in nascent DNAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Pittsburgh School of Medicine

Curated by ChEMBL
LigandPNGBDBM50118233(CHEMBL335538 | dATP | ATP,2'-deoxy | 2'-deoxya...)
Affinity DataKd:  7.50E+3nMAssay Description:Binding affinity to HIV1 wild type reverse transcriptase p66/p51 expressed in Escherichia coli assessed as incorporation of drug to DNA by gel electr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2X purinoceptor 2(Human)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50118233(CHEMBL335538 | dATP | ATP,2'-deoxy | 2'-deoxya...)
Affinity DataKi:  47.2nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2X purinoceptor 3(Human)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50118233(CHEMBL335538 | dATP | ATP,2'-deoxy | 2'-deoxya...)
Affinity DataKi:  180nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed