BDBM50118966 1-(7-Methoxy-2-phenyl-chroman-4-yl)-1H-imidazole::CHEMBL95109

SMILES COc1ccc2C(CC(Oc2c1)c1ccccc1)n1ccnc1

InChI Key InChIKey=JEQHTTKNYWNYDK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50118966   

TargetAromatase(Homo sapiens (Human))
Upres Ea 1085

Curated by ChEMBL
LigandPNGBDBM50118966(1-(7-Methoxy-2-phenyl-chroman-4-yl)-1H-imidazole |...)
Affinity DataIC50:  91nMAssay Description:Inhibition of aromatase activity in human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Upres Ea 1085

Curated by ChEMBL
LigandPNGBDBM50118966(1-(7-Methoxy-2-phenyl-chroman-4-yl)-1H-imidazole |...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibition of [1,2,6,7-3H]androstenedione binding to Aromatase of human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Upres Ea 1085

Curated by ChEMBL
LigandPNGBDBM50118966(1-(7-Methoxy-2-phenyl-chroman-4-yl)-1H-imidazole |...)
Affinity DataIC50:  60nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as inhibition of aromatization of [1,2,6,7-3H] androstenedione by flow scintillation a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Upres Ea 1085

Curated by ChEMBL
LigandPNGBDBM50118966(1-(7-Methoxy-2-phenyl-chroman-4-yl)-1H-imidazole |...)
Affinity DataIC50:  91nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as inhibition of aromatization of [1,2,6,7-3H] androstenedione by flow scintillation a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Upres Ea 1085

Curated by ChEMBL
LigandPNGBDBM50118966(1-(7-Methoxy-2-phenyl-chroman-4-yl)-1H-imidazole |...)
Affinity DataIC50:  91nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as inhibition of aromatization of [1,2,6,7-3H] androstenedione by flow scintillation a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed