BDBM50119234 4-Methyl-2-[2-(naphthalen-1-yloxy)-acetylamino]-pentanoic acid (2-hydroxy-5-oxo-tetrahydro-furan-3-yl)-amide::4-Methyl-2-[2-(naphthalen-2-yloxy)-acetylamino]-pentanoic acid (2-hydroxy-5-oxo-tetrahydro-furan-3-yl)-amide::CHEMBL318386

SMILES CC(C)C[C@H](NC(=O)COc1cccc2ccccc12)C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=UVJNVVPTQWFZMT-ASCMOBCVSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50119234   

TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119234(4-Methyl-2-[2-(naphthalen-1-yloxy)-acetylamino]-pe...)
Affinity DataIC50:  135nMAssay Description:Inhibitory concentration against caspase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119234(4-Methyl-2-[2-(naphthalen-1-yloxy)-acetylamino]-pe...)
Affinity DataIC50:  770nMAssay Description:Inhibitory concentration against caspase-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119234(4-Methyl-2-[2-(naphthalen-1-yloxy)-acetylamino]-pe...)
Affinity DataIC50:  940nMAssay Description:Inhibitory concentration required against caspase-6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119234(4-Methyl-2-[2-(naphthalen-1-yloxy)-acetylamino]-pe...)
Affinity DataIC50:  135nMAssay Description:Inhibitory concentration of compound required against Caspase-3 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119234(4-Methyl-2-[2-(naphthalen-1-yloxy)-acetylamino]-pe...)
Affinity DataIC50:  570nMAssay Description:Inhibition of caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119234(4-Methyl-2-[2-(naphthalen-1-yloxy)-acetylamino]-pe...)
Affinity DataIC50:  770nMAssay Description:Inhibitory concentration of compound required against Caspase-8 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119234(4-Methyl-2-[2-(naphthalen-1-yloxy)-acetylamino]-pe...)
Affinity DataIC50:  1.81E+3nMAssay Description:Inhibitory concentration of compound required against Caspase-7 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119234(4-Methyl-2-[2-(naphthalen-1-yloxy)-acetylamino]-pe...)
Affinity DataIC50:  570nMAssay Description:Inhibitory concentration of compound required against Caspase-1 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119234(4-Methyl-2-[2-(naphthalen-1-yloxy)-acetylamino]-pe...)
Affinity DataIC50:  1.81E+3nMAssay Description:Inhibitory concentration against caspase-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119234(4-Methyl-2-[2-(naphthalen-1-yloxy)-acetylamino]-pe...)
Affinity DataIC50:  940nMAssay Description:Inhibitory concentration of compound required against Caspase-6 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed