BDBM50119245 4-(2-Acetylamino-2-carboxy-acetylamino)-4-[1-(2-hydroxy-5-oxo-tetrahydro-furan-3-ylcarbamoyl)-2-methyl-propylcarbamoyl]-butyric acid::CHEMBL328412

SMILES CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(C)=O)C(O)=O)C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=INEQQSYFBJJTKI-FQAXKGDYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50119245   

TargetCaspase-7(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119245(4-(2-Acetylamino-2-carboxy-acetylamino)-4-[1-(2-hy...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration of compound required against Caspase-7 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119245(4-(2-Acetylamino-2-carboxy-acetylamino)-4-[1-(2-hy...)
Affinity DataIC50:  3.5nMAssay Description:Inhibitory concentration of compound required against Caspase-3 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119245(4-(2-Acetylamino-2-carboxy-acetylamino)-4-[1-(2-hy...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration of compound required against Caspase-1 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119245(4-(2-Acetylamino-2-carboxy-acetylamino)-4-[1-(2-hy...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration of compound required against Caspase-6 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119245(4-(2-Acetylamino-2-carboxy-acetylamino)-4-[1-(2-hy...)
Affinity DataIC50:  80nMAssay Description:Inhibitory concentration of compound required against Caspase-8 compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed