BDBM50119257 3-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbamoyl)-propylcarbamoyl]-methoxy}-naphthalene-2-carboxylic acid::CHEMBL328155

SMILES CC(C)C(NC(=O)COc1cc2ccccc2cc1C(O)=O)C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=JPRMMEXMBCGVFV-KATGSKEPSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50119257   

TargetCaspase-1(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119257(3-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbam...)
Affinity DataIC50:  1.89E+3nMAssay Description:Inhibition of Caspase-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119257(3-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbam...)
Affinity DataIC50:  731nMAssay Description:Inhibition of Caspase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119257(3-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbam...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Caspase-8 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119257(3-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbam...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of Caspase-7 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119257(3-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbam...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Caspase-6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed