BDBM50119286 3-Methoxy-7,8-dihydro-6H-5,10-dithia-8-aza-benzo[a]azulen-9-one::CHEMBL319170::PD-146626::kb-NB165-09
SMILES COc1ccc2sc3c(SCCNC3=O)c2c1
InChI Key InChIKey=KGMSYXGSYGEHIS-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50119286
Affinity DataIC50: 82.5nMpH: 7.5 T: 2°CAssay Description:In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.More data for this Ligand-Target Pair
Affinity DataIC50: 142nMpH: 7.5 T: 2°CAssay Description:In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.More data for this Ligand-Target Pair
Affinity DataIC50: 98.5nMpH: 7.5 T: 2°CAssay Description:In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.More data for this Ligand-Target Pair
Affinity DataIC50: 82.5nMAssay Description:Inhibition of human recombinant PKD1 after 10 mins by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of MK2 in human U937 cells assessed as blockade of LPS-stimulated TNFalpha productionMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of PKD1 autophosphorylation at Ser916 in human PMA-induced LNCAP cells by Western blottingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair