BDBM50119375 CHEMBL140612::N-(3-(4-(2-methoxyphenyl)piperazin-1-yl)propyl)H-pyrazolo[1,5-a]pyridine-3-carboxamide::Pyrazolo[1,5-a]pyridine-3-carboxylic acid {3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-amide

SMILES COc1ccccc1N1CCN(CCCNC(=O)c2cnn3ccccc23)CC1

InChI Key InChIKey=OLKYYLJXZLWORJ-UHFFFAOYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50119375   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119375(CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity for human Dopamine receptor D2 (short) by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119375(CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  11nMAssay Description:Binding affinity for human Dopamine receptor D2 (long) by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119375(CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119375(CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119375(CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119375(CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  14nMAssay Description:Binding affinity for human Dopamine receptor D4 by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119375(CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119375(CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  69nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119375(CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  150nMAssay Description:Binding affinity for human Dopamine receptor D3 by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119375(CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119375(CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  2.20E+3nMAssay Description:Binding affinity for porcine Dopamine receptor D1 by [3H]-SCH- 23390 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed