BDBM50119378 CHEMBL143352::N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)H-pyrazolo[1,5-a]pyridine-4-carboxamide::Pyrazolo[1,5-a]pyridine-4-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide

SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cccn3nccc23)CC1

InChI Key InChIKey=CXWMHNWEROVFMB-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50119378   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119378(CHEMBL143352 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]- 8-OH-DPAT from porcine 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119378(CHEMBL143352 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  20nMAssay Description:Binding affinity for human Dopamine receptor D3 by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119378(CHEMBL143352 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  87nMAssay Description:Binding affinity for human Dopamine receptor D4 by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119378(CHEMBL143352 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]ketanserin from human 5-HT2A receptor expressed in HEK293 cell membranes by radioligand competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119378(CHEMBL143352 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  180nMAssay Description:Binding affinity for human Dopamine receptor D2 (short) by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119378(CHEMBL143352 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  270nMAssay Description:Binding affinity for human Dopamine receptor D2 (long) by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119378(CHEMBL143352 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in CHO cell membranes by radioligand competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119378(CHEMBL143352 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity for porcine Dopamine receptor D1 by [3H]-SCH- 23390 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed