BDBM50119585 CHEMBL3617746::US10413545, Compound 95::US9718813, Compound 95
SMILES Cn1cc(cn1)-c1ccc(cc1)-c1ccc(C2=NC(C)(C)C(=O)N2C[C@@H]2CCN(C2)C(=O)C2(O)CC2)c(F)c1
InChI Key InChIKey=PXRDSWCMKCLNIA-LJQANCHMSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50119585
Affinity DataIC50: 30nMAssay Description:Inhibition of fatty acid synthase (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30.2nMAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair
Affinity DataIC50: 30.2nMpH: 7.5 T: 2°CAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair