BDBM50119931 2-[4-(4-chlorobenzyl)hexahydro-1-pyrazinyl]-1-spiro[cyclopentane-1,2'-(2',3'-dihydro-1'H-indole)]-1-yl-1-ethanone::CHEMBL441274

SMILES Clc1ccc(CN2CCN(CC(=O)N3c4ccccc4CC33CCCC3)CC2)cc1

InChI Key InChIKey=UXSXSSBOLOHWNU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119931   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50119931(2-[4-(4-chlorobenzyl)hexahydro-1-pyrazinyl]-1-spir...)
Affinity DataKi:  36nMAssay Description:Binding affinity towards human Dopamine Receptor D4 was determined via standard competitive displacement assays using [3H]-YM 09151 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50119931(2-[4-(4-chlorobenzyl)hexahydro-1-pyrazinyl]-1-spir...)
Affinity DataKi:  187nMAssay Description:Binding affinity towards human Dopamine receptor D2 was determined via standard competitive displacement assay using [3H]-YM 09151 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50119931(2-[4-(4-chlorobenzyl)hexahydro-1-pyrazinyl]-1-spir...)
Affinity DataKi:  909nMAssay Description:Binding affinity towards Alpha-1 adrenergic receptor via standard competitive displacement assay using rat brain homogenate with [3H]prazosin as radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed