BDBM50119972 2-[4-(5-Chloro-2-ethoxy-benzyl)-piperazin-1-yl]-1-((R)-2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL326863

SMILES CCOc1ccc(Cl)cc1CN1CCN(CC(=O)N2[C@H](C)Cc3ccccc23)CC1

InChI Key InChIKey=QSFIOZUTOJIBTH-GOSISDBHSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119972   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50119972(2-[4-(5-Chloro-2-ethoxy-benzyl)-piperazin-1-yl]-1-...)
Affinity DataKi:  11nMAssay Description:Binding affinity towards Dopamine type 4 receptor was determined by competitive displacement assays using [3H]-YM 09151 as the competitive ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50119972(2-[4-(5-Chloro-2-ethoxy-benzyl)-piperazin-1-yl]-1-...)
Affinity DataKi:  134nMAssay Description:Binding affinity towards Dopamine type 2 receptor was determined by displacement assays using [3H]-YM 09151 as the competitive ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50119972(2-[4-(5-Chloro-2-ethoxy-benzyl)-piperazin-1-yl]-1-...)
Affinity DataKi:  1.09E+6nMAssay Description:Binding affinity towards Alpha-1 adrenergic receptor was determined by competitive displacement assays using rat brain homogenate with [3H]prazosin a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed