BDBM50120692 2-{3-[4-(3,5-Dimethyl-benzyloxy)-phenyl]-3-methyl-2-oxo-pyrrolidin-1-yl}-N-hydroxy-propionamide::CHEMBL144548

SMILES C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2cc(C)cc(C)c2)cc1)C(=O)NO

InChI Key InChIKey=AHGKFZKBVGBMPT-HXOBKFHXSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120692   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120692(2-{3-[4-(3,5-Dimethyl-benzyloxy)-phenyl]-3-methyl-...)
Affinity DataKi:  1.63E+3nMAssay Description:Affinity towards Matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120692(2-{3-[4-(3,5-Dimethyl-benzyloxy)-phenyl]-3-methyl-...)
Affinity DataKi:  4.75E+3nMAssay Description:Affinity towards Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120692(2-{3-[4-(3,5-Dimethyl-benzyloxy)-phenyl]-3-methyl-...)
Affinity DataKi:  5.81E+3nMAssay Description:Affinity for Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120692(2-{3-[4-(3,5-Dimethyl-benzyloxy)-phenyl]-3-methyl-...)
Affinity DataIC50:  4nMAssay Description:Affinity for Tumor necrosis factor alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed