BDBM50120776 8-Benzyl-2-(2,4-difluoro-phenyl)-6,7,8,9-tetrahydro-5H-1,3a,5,8-tetraaza-cyclopenta[a]naphthalen-4-one::CHEMBL343009

SMILES Fc1ccc(-c2cn3c(n2)c2CN(Cc4ccccc4)CCc2[nH]c3=O)c(F)c1

InChI Key InChIKey=GDDQCBXGUOULOB-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120776   

TargetGamma-aminobutyric acid receptor subunit alpha-3(Homo sapiens (Human))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50120776(8-Benzyl-2-(2,4-difluoro-phenyl)-6,7,8,9-tetrahydr...)
Affinity DataEC50:  500nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50120776(8-Benzyl-2-(2,4-difluoro-phenyl)-6,7,8,9-tetrahydr...)
Affinity DataEC50:  210nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50120776(8-Benzyl-2-(2,4-difluoro-phenyl)-6,7,8,9-tetrahydr...)
Affinity DataEC50:  323nMAssay Description:Effective concentration against Gamma-aminobutyric acid A receptor, alpha 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50120776(8-Benzyl-2-(2,4-difluoro-phenyl)-6,7,8,9-tetrahydr...)
Affinity DataEC50:  92nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed