BDBM50121157 5-(3-Fluoro-5-nitro-phenyl)-3,3-dimethyl-1,3-dihydro-indol-2-one::CHEMBL115638

SMILES CC1(C)C(=O)Nc2ccc(cc12)-c1cc(F)cc(c1)[N+]([O-])=O

InChI Key InChIKey=FUWSBZPWEYZYPZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50121157   

TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121157(5-(3-Fluoro-5-nitro-phenyl)-3,3-dimethyl-1,3-dihyd...)
Affinity DataIC50:  27nMAssay Description:Progesterone receptor antagonist activity based on its ability to block progesterone induced alkaline phosphatase in the human breast cancer cell lin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed