BDBM50121162 5'-(3-chlorophenyl)spiro[cyclopropane-1,3'-indol]-2'(1'H)-one::CHEMBL331249

SMILES Clc1cccc(c1)-c1ccc2NC(=O)C3(CC3)c2c1

InChI Key InChIKey=VEZSAICRYRMJTF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121162   

TargetProgesterone receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50121162(5'-(3-chlorophenyl)spiro[cyclopropane-1,3'-indol]-...)
Affinity DataIC50:  85nMAssay Description:Antagonist activity at progesterone receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProgesterone receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50121162(5'-(3-chlorophenyl)spiro[cyclopropane-1,3'-indol]-...)
Affinity DataIC50:  85nMAssay Description:Progesterone receptor antagonist activity based on its ability to block progesterone induced alkaline phosphatase in the human breast cancer cell lin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed