BDBM50121166 5'-(3-nitrophenyl)spiro[cyclopentane-1,3'-indol]-2'(1'H)-one::CHEMBL419057

SMILES [O-][N+](=O)c1cccc(c1)-c1ccc2NC(=O)C3(CCCC3)c2c1

InChI Key InChIKey=AWTOGSZGTICREU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121166   

TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121166(5'-(3-nitrophenyl)spiro[cyclopentane-1,3'-indol]-2...)
Affinity DataIC50:  38nMAssay Description:Progesterone receptor antagonist activity based on its ability to block progesterone induced alkaline phosphatase in the human breast cancer cell lin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121166(5'-(3-nitrophenyl)spiro[cyclopentane-1,3'-indol]-2...)
Affinity DataIC50:  193nMAssay Description:Inhibition of 3 nM [3H]-R5020 binding to progesterone receptor of human T47D cell cytosolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed