BDBM50121178 5-(3,3-Dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-thiophene-2-carbonitrile::CHEMBL117954

SMILES CC1(C)C(=O)Nc2ccc(cc12)-c1ccc(s1)C#N

InChI Key InChIKey=IJZKPGCSGWNFLE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50121178   

TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121178(5-(3,3-Dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-t...)
Affinity DataIC50:  28nMAssay Description:Progesterone receptor antagonist activity based on its ability to block progesterone induced alkaline phosphatase in the human breast cancer cell lin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed