BDBM50121604 4-(2-{4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino}-6-[4-(2-methyl-thiazol-4-ylmethyl)-piperazin-1-yl]-[1,3,5]triazin-2-ylamino}-ethyl)-phenol::CHEMBL434502
SMILES CN(CCCc1ccc(Cl)cc1)c1nc(NCCc2ccc(O)cc2)nc(n1)N1CCN(Cc2csc(C)n2)CC1
InChI Key InChIKey=PVIFHDOPIPOZGE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50121604
Affinity DataKi: 25nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 650nMAssay Description:In vitro binding affinity towards human Estrogen receptor alpha using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:In vitro inhibition of transcriptional activation induced by 1 nM 17-beta estradiol in T47D cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Agonist effect on transcriptional activation in T47D cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of 1 nM 17-beta-estradiol induced transcriptional activation in T47D cells expressing estrogen receptor betaMore data for this Ligand-Target Pair