BDBM50121901 Acetic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-4-oxo-azetidin-2-yl ester::CHEMBL417303

SMILES CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=DTKJGQRHUHIVHR-UEXGIBASSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50121901   

TargetNeutrophil elastase(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121901(Acetic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human leukocyte elastase(HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121901(Acetic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamin...)
Affinity DataIC50:  470nMAssay Description:Inhibition of recombinant rat Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121901(Acetic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamin...)
Affinity DataIC50:  42nMAssay Description:Inhibition of recombinant human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121901(Acetic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamin...)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121901(Acetic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamin...)
Affinity DataIC50:  207nMAssay Description:Inhibition of recombinant human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed