BDBM50121908 3-Phenyl-propionic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-4-oxo-azetidin-2-yl ester::CHEMBL30356

SMILES O=C(CCc1ccccc1)O[C@@H]1NC(=O)[C@H]1NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=YYTYMENWZQHVGX-CKOJHNACSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50121908   

TargetProcathepsin L(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121908(3-Phenyl-propionic acid (2S,3S)-3-((S)-2-benzyloxy...)
Affinity DataIC50:  47nMAssay Description:Inhibition of recombinant human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121908(3-Phenyl-propionic acid (2S,3S)-3-((S)-2-benzyloxy...)
Affinity DataIC50:  38nMAssay Description:Inhibition of recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121908(3-Phenyl-propionic acid (2S,3S)-3-((S)-2-benzyloxy...)
Affinity DataIC50:  9.71E+3nMAssay Description:Inhibition of recombinant rat Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121908(3-Phenyl-propionic acid (2S,3S)-3-((S)-2-benzyloxy...)
Affinity DataIC50:  41nMAssay Description:Inhibition of recombinant human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121908(3-Phenyl-propionic acid (2S,3S)-3-((S)-2-benzyloxy...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human leukocyte elastase(HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed