BDBM50122184 CHEMBL296041::N-(3-Chloro-benzyl)-2-(6-methyl-2-oxo-3-phenylmethanesulfonylamino-2H-pyridin-1-yl)-acetamide

SMILES Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCc1cccc(Cl)c1

InChI Key InChIKey=OPLOHJRHPZEWDO-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50122184   

TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122184(CHEMBL296041 | N-(3-Chloro-benzyl)-2-(6-methyl-2-o...)
Affinity DataKi:  7nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122184(CHEMBL296041 | N-(3-Chloro-benzyl)-2-(6-methyl-2-o...)
Affinity DataKi:  7nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122184(CHEMBL296041 | N-(3-Chloro-benzyl)-2-(6-methyl-2-o...)
Affinity DataKi:  7.10nMAssay Description:Inhibitory constant evaluated against thrombin (Factor IIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122184(CHEMBL296041 | N-(3-Chloro-benzyl)-2-(6-methyl-2-o...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122184(CHEMBL296041 | N-(3-Chloro-benzyl)-2-(6-methyl-2-o...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibitory constant evaluated against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed