BDBM50122375 1-(2,6-Dichloro-phenyl)-5-(2,4-difluoro-phenyl)-7-(piperazine-1-carbonyl)-3,4-dihydro-1H-quinazolin-2-one::1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-(piperazine-1-carbonyl)-3,4-dihydroquinazolin-2(1H)-one::CHEMBL327217

SMILES Fc1ccc(c(F)c1)-c1cc(cc2N(C(=O)NCc12)c1c(Cl)cccc1Cl)C(=O)N1CCNCC1

InChI Key InChIKey=FBUWJQYMBWYMNV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50122375   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122375(1-(2,6-Dichloro-phenyl)-5-(2,4-difluoro-phenyl)-7-...)
Affinity DataIC50:  2.40nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122375(1-(2,6-Dichloro-phenyl)-5-(2,4-difluoro-phenyl)-7-...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of p38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122375(1-(2,6-Dichloro-phenyl)-5-(2,4-difluoro-phenyl)-7-...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed