BDBM50122377 5-(2-Chloro-4-fluoro-phenyl)-7-(1-cyclobutyl-piperidin-4-yl)-1-(2,6-dichloro-phenyl)-3,4-dihydro-1H-quinazolin-2-one::5-(2-chloro-4-fluorophenyl)-7-(1-cyclobutylpiperidin-4-yl)-1-(2,6-dichlorophenyl)-3,4-dihydroquinazolin-2(1H)-one::CHEMBL419140

SMILES Fc1ccc(c(Cl)c1)-c1cc(cc2N(C(=O)NCc12)c1c(Cl)cccc1Cl)C1CCN(CC1)C1CCC1

InChI Key InChIKey=BQFXJXUZORXVKT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50122377   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50122377(5-(2-Chloro-4-fluoro-phenyl)-7-(1-cyclobutyl-piper...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of p38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50122377(5-(2-Chloro-4-fluoro-phenyl)-7-(1-cyclobutyl-piper...)
Affinity DataIC50:  0.400nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed