BDBM50122378 5-(2-Chloro-phenyl)-1-(2,6-dichloro-phenyl)-7-piperazin-1-yl-3,4-dihydro-1H-quinazolin-2-one::5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-(piperazin-1-yl)-3,4-dihydroquinazolin-2(1H)-one::CHEMBL96487

SMILES Clc1ccccc1-c1cc(cc2N(C(=O)NCc12)c1c(Cl)cccc1Cl)N1CCNCC1

InChI Key InChIKey=CKLVALHGAAVVOI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50122378   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122378(5-(2-Chloro-phenyl)-1-(2,6-dichloro-phenyl)-7-pipe...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122378(5-(2-Chloro-phenyl)-1-(2,6-dichloro-phenyl)-7-pipe...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of p38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122378(5-(2-Chloro-phenyl)-1-(2,6-dichloro-phenyl)-7-pipe...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed