BDBM50122776 1-(4-Dimethylaminomethyl-phenyl)-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azulen-6-one::AG-014361::CHEMBL65892::cid_9840076

SMILES CN(C)Cc1ccc(cc1)-c1nc2cccc3C(=O)NCCn1c23

InChI Key InChIKey=SEKJSSBJKFLZIT-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50122776   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50122776(1-(4-Dimethylaminomethyl-phenyl)-8,9-dihydro-7H-2,...)
Affinity DataKi:  5.80nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50122776(1-(4-Dimethylaminomethyl-phenyl)-8,9-dihydro-7H-2,...)
Affinity DataEC50:  2.75E+4nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay