BDBM50123163 CHEMBL3622672::US9388160, 12
SMILES COc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1NC(=O)\C=C\CN1CCCCC1
InChI Key InChIKey=NAVGIMRWOWYNEP-DHZHZOJOSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50123163
TargetEpidermal growth factor receptor [668-1210,T790M,L858R](Homo sapiens (Human))
Teligene
US Patent
Teligene
US Patent
Affinity DataIC50: 22nMpH: 7.4 T: 2°CAssay Description:The assay was performed using Kinase-Glo Plus luminescence kinase assay kit (Promega). The compounds were diluted in 10% DMSO and 5 μl of the dilu...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of EGFR (unknown origin) by ELISA methodMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [668-1210,T790M,L858R](Homo sapiens (Human))
Teligene
US Patent
Teligene
US Patent
Affinity DataIC50: <100nMpH: 7.4 T: 2°CAssay Description:The assay was performed using Kinase-Glo Plus luminescence kinase assay kit (Promega). The compounds were diluted in 10% DMSO and 5 μl of the dilu...More data for this Ligand-Target Pair