BDBM50123420 7-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-phenyl}-methanesulfonyl-amino)-methyl]-naphthalene-2-carboxamidine::CHEMBL152069

SMILES CC(=N)N1CCC(CC1)Oc1ccc(cc1)N(Cc1ccc2ccc(cc2c1)C(N)=N)S(C)(=O)=O

InChI Key InChIKey=STGHZZUKURHQKO-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50123420   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Portola Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123420(7-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-pheny...)
Affinity DataKi:  3.90E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG potassium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123420(7-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-pheny...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of factor IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123420(7-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-pheny...)
Affinity DataIC50:  94nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123420(7-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-pheny...)
Affinity DataIC50:  6nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed