BDBM50123478 CHEMBL356296::N-(4-Chloro-pyridin-2-ylmethyl)-2-[3-(2,2-difluoro-2-phenyl-ethylamino)-6-methyl-2-oxo-2H-pyrazin-1-yl]-acetamide

SMILES Cc1cnc(NCC(F)(F)c2ccccc2)c(=O)n1CC(=O)NCc1cc(Cl)ccn1

InChI Key InChIKey=XEELLDSGGACWLV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123478   

TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123478(CHEMBL356296 | N-(4-Chloro-pyridin-2-ylmethyl)-2-[...)
Affinity DataKi:  1.30nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123478(CHEMBL356296 | N-(4-Chloro-pyridin-2-ylmethyl)-2-[...)
Affinity DataKi:  4.70E+4nMAssay Description:Inhibitory constant against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed