BDBM50123500 CHEMBL143139::N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-[6-methyl-3-(2-methyl-2-phenyl-propylamino)-2-oxo-2H-pyrazin-1-yl]-acetamide

SMILES Cc1nc(N)ccc1CNC(=O)Cn1c(C)cnc(NCC(C)(C)c2ccccc2)c1=O

InChI Key InChIKey=YTDWOXUEZRXCIH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50123500   

TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123500(CHEMBL143139 | N-(6-Amino-2-methyl-pyridin-3-ylmet...)
Affinity DataKi:  1.10nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123500(CHEMBL143139 | N-(6-Amino-2-methyl-pyridin-3-ylmet...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of Thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123500(CHEMBL143139 | N-(6-Amino-2-methyl-pyridin-3-ylmet...)
Affinity DataKi:  800nMAssay Description:Inhibitory constant against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed