BDBM50123679 CHEMBL3622745

SMILES CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(=O)CCc1ccccc1

InChI Key InChIKey=XPWZVZRASOIWHR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123679   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50123679(CHEMBL3622745)
Affinity DataKi:  220nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50123679(CHEMBL3622745)
Affinity DataIC50:  560nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed