BDBM50123973 3-{4-[3-(3,4-Dimethoxy-phenyl)-ureido]-phenyl}-N-hydroxy-acrylamide::CHEMBL148769::US8796330, 147
SMILES COc1ccc(NC(=O)Nc2ccc(\C=C\C(=O)NO)cc2)cc1OC
InChI Key InChIKey=YYJQTOKVRNZEPY-BJMVGYQFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50123973
Affinity DataIC50: 480nMT: 2°CAssay Description:For deacetylase assays, 20,000 cpm of the [3H]-metabolically labeled acetylated histone substrate (M. Yoshida et al., J. Biol. Chem. 265(28): 17174-1...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against human Histone deacetylase 1More data for this Ligand-Target Pair
Affinity DataEC50: >2.50E+4nMAssay Description:Inhibition of acetylation of histone-4 in human T-24 cancer cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity on partially purified recombinant human Histone deacetylase 1 (HDAC-1)More data for this Ligand-Target Pair