BDBM50124354 CHEMBL3623439

SMILES Oc1ccc(Nc2ncc(s2)-c2ccncc2-c2ccccc2Cl)cc1

InChI Key InChIKey=SEZBMVMOFIKXMB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124354   

TargetLIM domain kinase 2(Homo sapiens (Human))
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124354(CHEMBL3623439)
Affinity DataIC50:  1nMAssay Description:Inhibition of human N-terminal GST-tagged LIMK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124354(CHEMBL3623439)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of LIMK1 in human ZR75-1 cells assessed as inhibition of cofilin phosphorylation after 5 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124354(CHEMBL3623439)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed