BDBM50124914 CHEMBL161180::N-(3,5-Dichloro-benzyl)-4-trifluoromethoxy-benzamidine
SMILES NC(=NCc1cc(Cl)cc(Cl)c1)c1ccc(OC(F)(F)F)cc1
InChI Key InChIKey=HCUDNPNQOOAXTQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50124914
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2A subtype was determined using FLIPR assayMore data for this Ligand-Target Pair