BDBM50124922 4-Chloro-N-(3-chloro-benzyl)-benzamidine::CHEMBL161871

SMILES NC(=NCc1cccc(Cl)c1)c1ccc(Cl)cc1

InChI Key InChIKey=LGIMDWHICRDCBI-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124922   

TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124922(4-Chloro-N-(3-chloro-benzyl)-benzamidine | CHEMBL1...)
Affinity DataKi:  63nMAssay Description:Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124922(4-Chloro-N-(3-chloro-benzyl)-benzamidine | CHEMBL1...)
Affinity DataIC50:  160nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed