BDBM50125442 1-[2-(3-Hydroxy-pyrrolidin-1-yl)-1-phenyl-ethyl]-3-(2-methoxy-phenyl)-1H-pyridin-2-one::CHEMBL15034

SMILES COc1ccccc1-c1cccn(C(CN2CCC(O)C2)c2ccccc2)c1=O

InChI Key InChIKey=MGVFKHIJORWPIN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50125442   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50125442(1-[2-(3-Hydroxy-pyrrolidin-1-yl)-1-phenyl-ethyl]-3...)
Affinity DataIC50:  94nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50125442(1-[2-(3-Hydroxy-pyrrolidin-1-yl)-1-phenyl-ethyl]-3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [125I]-Deltorphin binding to human delta opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed