BDBM50125450 (3-{1-[2-Oxo-3-(4-trifluoromethyl-phenyl)-2H-pyridin-1-yl]-2-pyrrolidin-1-yl-ethyl}-phenoxy)-acetic acid::CHEMBL15429

SMILES OC(=O)COc1cccc(c1)C(CN1CCCC1)n1cccc(-c2ccc(cc2)C(F)(F)F)c1=O

InChI Key InChIKey=PNPULJCRZWFKKS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50125450   

TargetDelta-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50125450((3-{1-[2-Oxo-3-(4-trifluoromethyl-phenyl)-2H-pyrid...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of [125I]-Deltorphin binding to human delta opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50125450((3-{1-[2-Oxo-3-(4-trifluoromethyl-phenyl)-2H-pyrid...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [125I]-Enkephalin binding to human mu opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50125450((3-{1-[2-Oxo-3-(4-trifluoromethyl-phenyl)-2H-pyrid...)
Affinity DataIC50:  420nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed