BDBM50125618 3-(3-Chloro-4-fluoro-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one::CHEMBL279268
SMILES CC1(O)OC(=O)C(=C1c1ccc(cc1)S(C)(=O)=O)c1ccc(F)c(Cl)c1
InChI Key InChIKey=OQDKPQRAGXTOIK-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50125618
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibitory concentration of the compound was measured against Prostaglandin G/H synthase 1 in the sensitive U937 microsome assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory concentration of the compound was measured against Prostaglandin G/H synthase 2 in human whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibitory of human Prostaglandin G/H synthase 2 expressed in CHO cells.More data for this Ligand-Target Pair