BDBM50126386 (1R,2S)-2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperazin-1-yl)methyl)-1,2,3,4-tetrahydronaphthalen-1-ol::2-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-piperazin-1-ylmethyl)-1,2,3,4-tetrahydro-naphthalen-1-ol::CHEMBL28660

SMILES O[C@@H]1[C@H](CN2CCN(CCOC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)CCc2ccccc12

InChI Key InChIKey=JLRAWBWOQSHDSR-ABYGYWHVSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50126386   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126386((1R,2S)-2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126386((1R,2S)-2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]RTI55 from DAT in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Heights

Curated by ChEMBL
LigandPNGBDBM50126386((1R,2S)-2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl...)
Affinity DataKi:  30nMAssay Description:Displacement of [125I]RTI55 from SERT in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Heights

Curated by ChEMBL
LigandPNGBDBM50126386((1R,2S)-2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl...)
Affinity DataKi:  30nMAssay Description:Binding affinity towards rat serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed