BDBM50126414 CHEMBL30240::N*1*-[7-(4-Chloro-phenyl)-[1,6]naphthyridin-5-yl]-propane-1,3-diamine::N1-(7-(4-chlorophenyl)-1,6-naphthyridin-5-yl)propane-1,3-diamine

SMILES NCCCNc1nc(cc2ncccc12)-c1ccc(Cl)cc1

InChI Key InChIKey=DXEHNIYDJMSTON-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50126414   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126414(CHEMBL30240 | N*1*-[7-(4-Chloro-phenyl)-[1,6]napht...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against spleen tyrosine kinase (SYK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126414(CHEMBL30240 | N*1*-[7-(4-Chloro-phenyl)-[1,6]napht...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of SYKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126414(CHEMBL30240 | N*1*-[7-(4-Chloro-phenyl)-[1,6]napht...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of recombinant Syk (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed