BDBM50126780 CHEMBL30993::Cyano-[5-fluoro-1-(4-methyl-benzyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]-acetic acid

SMILES Cc1ccc(CN2C(=O)C(C(C#N)C(O)=O)c3cc(F)ccc23)cc1

InChI Key InChIKey=CUKXYRVTVMBQCR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50126780   

TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50126780(CHEMBL30993 | Cyano-[5-fluoro-1-(4-methyl-benzyl)-...)
Affinity DataIC50:  75nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50126780(CHEMBL30993 | Cyano-[5-fluoro-1-(4-methyl-benzyl)-...)
Affinity DataIC50:  690nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50126780(CHEMBL30993 | Cyano-[5-fluoro-1-(4-methyl-benzyl)-...)
Affinity DataIC50:  75nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed