BDBM50127306 5-[(5-Cyano-3'-trifluoromethoxy-biphenyl-2-ylmethoxy)-(3-methyl-3H-imidazol-4-yl)-methyl]-pyridine-2-carbonitrile::CHEMBL38615

SMILES Cn1cncc1C(OCc1ccc(cc1-c1cccc(OC(F)(F)F)c1)C#N)c1ccc(nc1)C#N

InChI Key InChIKey=ZCOVCZOOFBWXSI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127306   

LigandPNGBDBM50127306(5-[(5-Cyano-3'-trifluoromethoxy-biphenyl-2-ylmetho...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127306(5-[(5-Cyano-3'-trifluoromethoxy-biphenyl-2-ylmetho...)
Affinity DataIC50:  990nMAssay Description:Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine GGTase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed