BDBM50127311 5-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-6-(4-trifluoromethoxy-phenyl)-pyridine-2-carbonitrile::CHEMBL39096
SMILES Cn1cncc1C(OCc1ccc(nc1-c1ccc(OC(F)(F)F)cc1)C#N)c1ccc(cc1)C#N
InChI Key InChIKey=PRTIQKLSEBTSEX-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50127311
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.510nMAssay Description:Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine GGTase-IMore data for this Ligand-Target Pair