BDBM50127392 3-(4-Chloro-3-methyl-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL50858
SMILES COC(=O)C1C2CC[C@H](C[C@@H]1c1ccc(Cl)c(C)c1)N2C
InChI Key InChIKey=VMITZEMDDZVHBZ-KCNJBTMXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50127392
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.950nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Inhibition of [3H]nisoxetine binding at norepinephrine transporter was determinedMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 0.810nMAssay Description:Inhibition of [3H]WIN-35428 binding at dopamine transporter was determinedMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of dopamine (DA) reuptake using cloned human dopamine transporter was determinedMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Norepinephrine (NA) reuptake using cloned human Norepinephrine transporter was determinedMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of [3H]nisoxetine binding at norepinephrine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair