BDBM50127392 3-(4-Chloro-3-methyl-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL50858

SMILES COC(=O)C1C2CC[C@H](C[C@@H]1c1ccc(Cl)c(C)c1)N2C

InChI Key InChIKey=VMITZEMDDZVHBZ-KCNJBTMXSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50127392   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127392(3-(4-Chloro-3-methyl-phenyl)-8-methyl-8-aza-bicycl...)
Affinity DataKi:  0.950nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127392(3-(4-Chloro-3-methyl-phenyl)-8-methyl-8-aza-bicycl...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of [3H]nisoxetine binding at norepinephrine transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127392(3-(4-Chloro-3-methyl-phenyl)-8-methyl-8-aza-bicycl...)
Affinity DataIC50:  0.810nMAssay Description:Inhibition of [3H]WIN-35428 binding at dopamine transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127392(3-(4-Chloro-3-methyl-phenyl)-8-methyl-8-aza-bicycl...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of dopamine (DA) reuptake using cloned human dopamine transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127392(3-(4-Chloro-3-methyl-phenyl)-8-methyl-8-aza-bicycl...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of Norepinephrine (NA) reuptake using cloned human Norepinephrine transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127392(3-(4-Chloro-3-methyl-phenyl)-8-methyl-8-aza-bicycl...)
Affinity DataIC50:  1nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127392(3-(4-Chloro-3-methyl-phenyl)-8-methyl-8-aza-bicycl...)
Affinity DataIC50:  36nMAssay Description:Inhibition of [3H]nisoxetine binding at norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127392(3-(4-Chloro-3-methyl-phenyl)-8-methyl-8-aza-bicycl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed