BDBM50127607 (1R,2R)-2-(1H-Imidazol-4-yl)-cyclopropylamine::(1R,2R)-2-(3H-Imidazol-4-yl)-cyclopropylamine::2-(1H-Imidazol-4-yl)-cyclopropylamine::CHEMBL13559::VUF-5296

SMILES N[C@@H]1C[C@H]1c1cnc[nH]1

InChI Key InChIKey=OWWNABDDYQLERE-RFZPGFLSSA-N

Data  5 KI  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50127607   

TargetHistamine H3 receptor(Rattus norvegicus (rat))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50127607((1R,2R)-2-(1H-Imidazol-4-yl)-cyclopropylamine | (1...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity of compound against Histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50127607((1R,2R)-2-(1H-Imidazol-4-yl)-cyclopropylamine | (1...)
Affinity DataKi:  25nMAssay Description:In vitro binding affinity was measured against Histamine H3 receptor on rat cerebral cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50127607((1R,2R)-2-(1H-Imidazol-4-yl)-cyclopropylamine | (1...)
Affinity DataKi:  42nMAssay Description:Affinity against rat Histamine H3 receptor using [3H]-N-alpha-methyl histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50127607((1R,2R)-2-(1H-Imidazol-4-yl)-cyclopropylamine | (1...)
Affinity DataKi:  68nMAssay Description:Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50127607((1R,2R)-2-(1H-Imidazol-4-yl)-cyclopropylamine | (1...)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50127607((1R,2R)-2-(1H-Imidazol-4-yl)-cyclopropylamine | (1...)
Affinity DataEC50:  724nMAssay Description:Inhibition of human Histamine H3 receptor using [3H]-N-alpha-methyl histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127607((1R,2R)-2-(1H-Imidazol-4-yl)-cyclopropylamine | (1...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H1 receptor using [3H]-pyrilamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50127607((1R,2R)-2-(1H-Imidazol-4-yl)-cyclopropylamine | (1...)
Affinity DataEC50:  58nMAssay Description:Inhibitory activity determined by the inhibition of cAMP- stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50127607((1R,2R)-2-(1H-Imidazol-4-yl)-cyclopropylamine | (1...)
Affinity DataEC50: <1.00E+4nMAssay Description:Inhibitory activity determined by the inhibition of cAMP- stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50127607((1R,2R)-2-(1H-Imidazol-4-yl)-cyclopropylamine | (1...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127607((1R,2R)-2-(1H-Imidazol-4-yl)-cyclopropylamine | (1...)
Affinity DataEC50:  2.50E+3nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]-tiotidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed